GROWTH HORMONE FRAGMENT PEPTIDE

AOP-9604™

AOD 9604 · TYR-HGH FRAGMENT 176-191 · 5 MG

AOP-9604™ is AOD 9604, the C-terminal lipolytic fragment of human growth hormone (residues 176–191) with an added N-terminal tyrosine. Supplied as lyophilised powder in vials of 5 mg, packed 3 vials per foil sachet for wholesale distribution.

RESEARCH KEYPOINT  Research found the benefit of AOD 9604 in helping reduce body weight gain and increase fat oxidation in obese mice, without the effects on insulin sensitivity and IGF-1 seen with full-length growth hormone.

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FOR EXPORT ONLY FOR RESEARCH AND ANALYTICS ONLY
AOP-9604 AOD 9604 Tyr-hGH fragment 176-191 5 mg sachet label, 3 vials per sachet

ABOUT AOP-9604

The lipolytic fragment of human growth hormone

AOD 9604 is a modified fragment of human growth hormone corresponding to amino acids 176–191 of the hGH C-terminus, with a tyrosine residue added at the N-terminus. The 176–191 region was identified in the 1990s as the part of the hormone associated with fat metabolism, and AOD 9604 was developed at Monash University as a stabilised analogue of that domain.

Published work has examined the fragment in relation to lipolysis, fat oxidation and body weight in rodent models, and has reported that it does not reproduce the effects of full-length growth hormone on IGF-1 levels or insulin sensitivity. AOP-9604™ supplies AOD 9604 as a defined, batch-documented reference material with identity and purity verified on every lot.

17AA

TYR + HGH 176-191

5 MG

PER VIAL

2–8°C

COLD CHAIN

DNA double helix illustration representing peptide regulation of gene expression

RESEARCH BACKGROUND

A fragment studied in lipid metabolism models

A 2001 study in Endocrinology compared chronic treatment with human growth hormone and with its lipolytic fragment AOD9604 in obese mice and in β3-adrenergic receptor knock-out mice. Both reduced body weight gain and increased lipolytic activity in adipose tissue, and the fragment increased fat oxidation without the changes in insulin sensitivity or IGF-1 associated with the full-length hormone.

Earlier metabolic work on the synthetic lipolytic domain of hGH reported comparable effects on fat metabolism, and the β3-AR knock-out arm of the 2001 study indicates the response does not depend on that receptor alone. Findings to date are preclinical, in cell and animal models.

PRIMARY REFERENCE

Heffernan MA, Thorburn AW, Fam B, et al. The effects of human GH and its lipolytic fragment (AOD9604) on lipid metabolism following chronic treatment in obese mice and β3-AR knock-out mice. Endocrinology. 2001;142(12):5182–5189.

Department of Medicine, Monash University, Melbourne

DOI: 10.1210/ENDO.142.12.8522

Reference provided for scientific context only. AOP-9604™ is analytical grade, for research and analytics only, and is not a medicinal product or dietary supplement. CoreyPauling is not affiliated with the cited authors.

PRODUCT SPECIFICATIONS

AOP-9604™ at a glance

Product name AOP-9604™
Active substance AOD 9604 — Tyr-hGH fragment 176-191
Strength 5 mg per vial
Form Lyophilised powder for reconstitution
Presentation Multi-dose glass vial
Pack size 3 vials per foil sachet
Origin Synthetic peptide fragment, produced by solid-phase peptide synthesis
Storage Store cold at 2–8°C; stable refrigerated for full shelf life, near-stable over 90 days at room temperature
Intended use Analytical grade · For research and analytics only · For export only
Documentation Batch-specific Certificate of Analysis
RESEARCH KEYPOINT Research found the benefit of AOD 9604 in helping reduce body weight gain and increase fat oxidation, reported in the 2001 Endocrinology study of chronic treatment in obese mice (Heffernan et al., Monash University).

OUR TECHNOLOGY

Pressurized Dark-Room Fragmented Lyophilization

AOP-9604™ is lyophilised using CoreyPauling's proprietary Pressurized Dark-Room Fragmented Lyophilization process, which protects the peptide from light and oxidative stress during freeze-drying — critical for a growth hormone fragment whose value lies in its intact sequence. The result is stability that conventional lyophilisates cannot match.

90+ days

Near-stable at room temperature

The lyophilised powder remains almost fully stable for over 90 days at room temperature — forgiving of transit delays and customs holds without loss of integrity.

3 years

Stable in cold storage

Stored cold at 2–8°C, AOP-9604™ retains full stability for the shelf life stated on every label, from the date of manufacture.

AOP-9604™ is analytical grade only. CoreyPauling does not encourage or support its use in humans or veterinary applications.

QUALITY & MANUFACTURING

Every batch documented

STD

International standards

Manufactured under internationally recognised quality standards with controlled environments and validated processes at every production step.

HPLC

Analytical verification

Identity, purity and content are verified by HPLC and complementary analytical methods before any batch is released.

LOT

Full traceability

Lot, manufacturing and expiry data are printed on every sachet and vial, tied to batch records and the Certificate of Analysis.

STORAGE & HANDLING

Cold chain, door to door

Store cold at 2–8°C

Keep refrigerated for full shelf life. Do not freeze. Protect vials from light and keep them in the original sachet until use; brief room-temperature excursions are tolerated thanks to our lyophilization process.

Insulated export shipping

Wholesale consignments ship in insulated packaging with cooling elements and temperature indicators, with export documentation prepared per destination.

FAQ

Frequently Asked Questions

AOP-9604™ is available exclusively through authorized retailers and distributors. Contact our wholesale team to be directed to an authorized retailer in your region.

No. CoreyPauling supplies wholesale quantities to distributors and authorized retailers only.

MOQ depends on destination and packaging configuration. Standard wholesale units are sachets of 3 vials; contact us with your required volume for tiered pricing.

Yes. Every batch ships with a batch-specific Certificate of Analysis covering identity, purity and content, referenced to the lot number printed on the sachet and vial labels.

Commercial invoice, packing list and Certificate of Analysis are standard. Additional documentation can be prepared according to the import requirements of the destination country.

CoreyPauling laboratory and lyophilization facility

ABOUT COREYPAULING

Science · Innovation · Quality · Trust

CoreyPauling is a US–Singapore based biotechnology company developing and supplying research-grade peptides and proteins to distributors and laboratories worldwide. Grounded in scientific rigour and international manufacturing standards, the brand stands for precision, continuous innovation and long-term reliability.

AOP-9604™ sits alongside the wider CoreyPauling catalogue — including Somapin™, Bepeci™, Retatride™, Tesamore™, Thymob™, Lorenpickart™, Kaypv™, Menotrope™, Igtrin™, Glutatone™ and Pregnil™ — all supplied under the same documentation and cold-chain standards.

Every batch of AOP-9604™ is manufactured at the CoreyPauling facility. Full company information, the complete product catalogue and manufacturing capabilities are available on the official factory website at coreypauling.com.

VISIT COREYPAULING.COM

WHOLESALE INQUIRY

Distribute AOP-9604™

For quotations, batch documentation, certificates of analysis and export terms, contact our wholesale team. Please include your company details, destination country and required quantities.

support@coreypauling.com
For Research and Analytics Only